mouse RARB Over-expression AAV

Name 
AAV-m-RARB
Cat No 
AAV-270149
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Rarb.

AAV-270149
AAV-m-RARB

Ready-to-use AAV expressing Mouse Rarb (retinoic acid receptor, beta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
A830025K23; Hap; Nr1b2
Description (Vector)
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function.
Gene ID
218772
Gene Name (Vector)
retinoic acid receptor, beta
Gene Symbol
Rarb
ORF Size (aa)
1347
ORF Size (bp)
1347 bp
RefSeq ID
NM_011243
RefSeq Synonyms
NM_011243, NM_001289762, NM_001289761, NM_001289760, BC076597,
Species
mouse
UniGene ID
Mm.259318

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.