mouse PTGDS Over-expression AAV
This is an AAV expressing Mouse Ptgds.
AAV-269734
AAV-m-PTGDS
Ready-to-use AAV expressing Mouse Ptgds (prostaglandin D2 synthase (brain)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
21kDa; L-PGDS; PGD2; PGDS; PGDS2; Ptgs3
Description (Vector)
Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophopic molecules and as a secretory retinoid and thyroid hormone transporter. Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system.
Gene ID
19215
Gene Name (Vector)
prostaglandin D2 synthase (brain)
Gene Symbol
Ptgds
ORF Size (aa)
570
ORF Size (bp)
570 bp
RefSeq ID
NM_008963
RefSeq Synonyms
NM_008963, BC043015, BC038083,
Species
mouse
UniGene ID
Mm.1008
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.