mouse PIN1 Over-expression AAV

Name 
AAV-m-PIN1
Cat No 
AAV-268672
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Pin1.

AAV-268672
AAV-m-PIN1

Ready-to-use AAV expressing Mouse Pin1 (protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
0610025L01Rik; D9Bwg1161e
Description (Vector)
Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzes pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation.
Gene ID
23988
Gene Name (Vector)
protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1
Gene Symbol
Pin1
ORF Size (aa)
498
RefSeq ID
NM_023371
RefSeq Synonyms
NM_023371, BC038254,
Species
mouse
UniGene ID
Mm.7906

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.