mouse NKRF Over-expression AAV

Name 
AAV-m-NKRF
Cat No 
AAV-265807
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Nkrf.

AAV-265807
AAV-m-NKRF

Ready-to-use AAV expressing Mouse Nkrf (NF-kappaB repressing factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
9430034D17Rik; AW124770; C80287
Description (Vector)
Interacts with a specific negative regulatory element (NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes. Involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity. Also involved in the regulation of IL-8 transcription.
Gene ID
77286
Gene Name (Vector)
NF-kappaB repressing factor
Gene Symbol
Nkrf
ORF Size (aa)
2073
ORF Size (bp)
2073 bp
RefSeq ID
NM_029891
RefSeq Synonyms
NM_029891, BC138829, BC138828,
Species
mouse
UniGene ID
Mm.21649

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.