mouse MYCN Over-expression AAV

Name 
AAV-m-MYCN
Cat No 
AAV-265263
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Mycn.

AAV-265263
AAV-m-MYCN

Ready-to-use AAV expressing Mouse Mycn (v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
bHLHe37; c-nmyc; neuroblastoma myc-related oncogene 1; Nmyc; N-myc; N-myc proto-oncogene protein; Nmyc1; Nmyc-1; v-myc myelocytomatosis viral related oncogene, neuroblastoma derived
Description (eCommerce)
N-Myc is a member of the Myc family of proteins which include c-Myc, N-Myc, and L-Myc. Myc family members are transactivating DNA binding proteins with oncogenic potential. Transactivation by Myc requires dimerization with other basic helix-loop-helix transcription factors. N-myc dimerizes with the MAX transcription factor.
Description (Vector)
MYCN may function as a transcription factor.
Gene ID
18109
Gene Name (eCommerce)
v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived
Gene Name (Vector)
v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived
Gene Symbol
Mycn
NCBI Taxonomy ID (eCommerce)
10090.0
ORF Size (aa)
1389
ORF Size (bp)
1389 bp
Protein Name (eCommerce)
N-myc proto-oncogene protein
RefSeq ID
NM_008709
RefSeq Synonyms
NM_008709, BC049783, BC005453,
Research Areas
Cancer,Phospho-specific,Tumor Suppressors/Oncoproteins
Research Areas (Faceted)
cancer,cell_biology
Species
mouse
Target Sentence
N-Myc is a member of the Myc family of proteins which include c-Myc, N-Myc, and L-Myc. Myc family members are transactivating DNA binding proteins with oncogenic potential. Transactivation by Myc requires dimerization with other basic helix-loop-helix transcription factors. N-myc dimerizes with the MAX transcription factor.
UniGene ID
Mm.16469
UniProt ID (eCommerce)
P03966

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.