mouse MYCN shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Mycn.
shAAV-265264
AAV-m-MYCN-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Mycn (v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
bHLHe37; c-nmyc; neuroblastoma myc-related oncogene 1; Nmyc; N-myc; N-myc proto-oncogene protein; Nmyc1; Nmyc-1; v-myc myelocytomatosis viral related oncogene, neuroblastoma derived
Description (eCommerce)
N-Myc is a member of the Myc family of proteins which include c-Myc, N-Myc, and L-Myc. Myc family members are transactivating DNA binding proteins with oncogenic potential. Transactivation by Myc requires dimerization with other basic helix-loop-helix transcription factors. N-myc dimerizes with the MAX transcription factor.
Description (Vector)
MYCN may function as a transcription factor.
Gene ID
18109
Gene Name (eCommerce)
v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived
Gene Name (Vector)
v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived
Gene Symbol
Mycn
NCBI Taxonomy ID (eCommerce)
10090.0
ORF Size (aa)
1389
ORF Size (bp)
1389 bp
Protein Name (eCommerce)
N-myc proto-oncogene protein
RefSeq ID
NM_008709
RefSeq Synonyms
NM_008709, BC049783, BC005453,
Research Areas
Cancer,Phospho-specific,Tumor Suppressors/Oncoproteins
Research Areas (Faceted)
cancer,cell_biology
Species
mouse
Target Sentence
N-Myc is a member of the Myc family of proteins which include c-Myc, N-Myc, and L-Myc. Myc family members are transactivating DNA binding proteins with oncogenic potential. Transactivation by Myc requires dimerization with other basic helix-loop-helix transcription factors. N-myc dimerizes with the MAX transcription factor.
UniGene ID
Mm.16469
UniProt ID (eCommerce)
P03966
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.