mouse MICAL1 Over-expression AAV

Name 
AAV-m-MICAL1
Cat No 
AAV-264623
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Mical1.

AAV-264623
AAV-m-MICAL1

Ready-to-use AAV expressing Mouse Mical1 (microtubule associated monooxygenase, calponin and LIM domain containing 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
MICAL; MICAL-1; Nical
Description (Vector)
Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin. Acts by modifying actin subunits through the addition of oxygen to form methionine-sulfoxide, leading to promote actin filament severing and prevent repolymerization (Probable). Acts as a cytoskeletal regulator that connects NEDD9 to intermediate filaments. Also acts as a negative regulator of apoptosis via its interaction with STK38 and STK38L; acts by antagonizing STK38 and STK38L activation by MST1/STK4.
Gene ID
171580
Gene Name (Vector)
microtubule associated monooxygenase, calponin and LIM domain containing 1
Gene Symbol
Mical1
ORF Size (aa)
3147
ORF Size (bp)
3147 bp
RefSeq ID
NM_138315
RefSeq Synonyms
NM_138315, NM_001164433, BC034682, BC021477,
Species
mouse
UniGene ID
Mm.290431

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.