mouse MICAL1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Mical1.
shADV-264623
Ad-m-MICAL1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Mical1 (microtubule associated monooxygenase, calponin and LIM domain containing 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MICAL; MICAL-1; Nical
Description (Vector)
Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin. Acts by modifying actin subunits through the addition of oxygen to form methionine-sulfoxide, leading to promote actin filament severing and prevent repolymerization (Probable). Acts as a cytoskeletal regulator that connects NEDD9 to intermediate filaments. Also acts as a negative regulator of apoptosis via its interaction with STK38 and STK38L; acts by antagonizing STK38 and STK38L activation by MST1/STK4.
Gene ID
171580
Gene Name (Vector)
microtubule associated monooxygenase, calponin and LIM domain containing 1
Gene Symbol
Mical1
ORF Size (aa)
3147
ORF Size (bp)
3147 bp
RefSeq ID
NM_138315
RefSeq Synonyms
NM_138315, NM_001164433, BC034682, BC021477,
Species
mouse
UniGene ID
Mm.290431
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.