mouse MAN1B1 Over-expression AAV

Name 
AAV-m-MAN1B1
Cat No 
AAV-264149
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Man1b1.

AAV-264149
AAV-m-MAN1B1

Ready-to-use AAV expressing Mouse Man1b1 (mannosidase, alpha, class 1B, member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
E430019H13Rik; ERMan1; Gm108; MANA-ER
Description (Vector)
Involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. It primarily trims a single alpha-1,2-linked mannose residue from Man(9)GlcNAc(2) to produce Man(8)GlcNAc(2), but at high enzyme concentrations, as found in the ER quality control compartment (ERQC), it further trims the carbohydrates to Man(5-6)GlcNAc(2).
Gene ID
227619
Gene Name (Vector)
mannosidase, alpha, class 1B, member 1
Gene Symbol
Man1b1
ORF Size (aa)
1977
ORF Size (bp)
1977 bp
RefSeq ID
NM_001029983
RefSeq Synonyms
NM_001029983, BC138551, BC138550,
Species
mouse
UniGene ID
Mm.270798

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.