mouse MAGED1 Over-expression AAV

Name 
AAV-m-MAGED1
Cat No 
AAV-264112
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Maged1.

AAV-264112
AAV-m-MAGED1

Ready-to-use AAV expressing Mouse Maged1 (melanoma antigen, family D, 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2810433C11Rik; 5430405L04Rik; Dlixin; Dlxin-1; Dlxin1; DXBwg1492e; MAGE-D1; mFLJ00163; NRAGE
Description (Vector)
Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Binds NGFR/p75NTR and antagonizes its association with NTRK1/TrkA, inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May regulate TP53/p53 transcriptional activity and inhibit cell proliferation. Enhances TP53 phosphorylation and accumulation. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex.
Gene ID
94275
Gene Name (Vector)
melanoma antigen, family D, 1
Gene Symbol
Maged1
ORF Size (aa)
1653
ORF Size (bp)
1653 bp
RefSeq ID
NM_019791
RefSeq Synonyms
NM_019791, BC031461, BC016438,
Species
mouse
UniGene ID
Mm.27578

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.