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human MAGED1 shRNA silencing Adenovirus

Name 
Ad-h-MAGED1-shRNA
Cat No 
shADV-214838
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human MAGED1.

shADV-214838
Ad-h-MAGED1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human MAGED1 (MAGE family member D1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
DLXIN-1; NRAGE
Description (Vector)
MAGED1 is a member of the melanoma antigen gene (MAGE) family. Most of the genes of this family encode tumor specific antigens that are not expressed in normal adult tissues except testis. Although the protein encoded by this gene shares strong homology with members of the MAGE family, it is expressed in almost all normal adult tissues. MAGED1 has been demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway. Three transcript variants encoding two different isoforms have been found for this gene.
Gene ID
9500
Gene Name (Vector)
MAGE family member D1
Gene Symbol
MAGED1
HGNC ID
HGNC:6813
ORF Size (aa)
2337
ORF Size (bp)
2337 bp
RefSeq ID
NM_006986
RefSeq Synonyms
NM_006986, NM_001005333, NM_001005332, BC032473, BC014070,
Species
human
UniGene ID
Hs.5258

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.