mouse MAFB Over-expression AAV

Name 
AAV-m-MAFB
Cat No 
AAV-264083
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Mafb.

AAV-264083
AAV-m-MAFB

Ready-to-use AAV expressing Mouse Mafb (v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
kr; Kreisler; Krml; Krml1
Description (Vector)
Acts as a transcriptional activator or repressor. Plays a pivotal role in regulating lineage-specific hematopoiesis by repressing ETS1-mediated transcription of erythroid-specific genes in myeloid cells. Required for monocytic, macrophage, podocyte and islet beta cell differentiation. Involved in renal tubule survival and F4/80 maturation. Activates the insulin and glucagon promoters. Together with PAX6, transactivates weakly the glucagon gene promoter through the G1 element. SUMO modification controls its transcriptional activity and ability to specify macrophage fate. Binds element G1 on the glucagon promoter (By similarity). Involved either as an oncogene or as a tumor suppressor, depending on the cell context.
Gene ID
16658
Gene Name (Vector)
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)
Gene Symbol
Mafb
ORF Size (aa)
972
ORF Size (bp)
972 bp
RefSeq ID
NM_010658
RefSeq Synonyms
NM_010658, BC038256, BC016434,
Species
mouse
UniGene ID
Mm.330745

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.