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mouse HACE1 Over-expression AAV

Name 
AAV-m-HACE1
Cat No 
AAV-261082
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Hace1.

AAV-261082
AAV-m-HACE1

Ready-to-use AAV expressing Mouse Hace1 (HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
1700042J16Rik; A730034A22Rik; BC025474
Description (Vector)
E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Acts as a regulator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab proteins and regulates postmitotic Golgi membrane fusion. Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division. Specifically interacts with GTP-bound RAC1, mediating ubiquitination and subsequent degradation of active RAC1, thereby playing a role in host defense against pathogens. May also act as a transcription regulator via its interaction with RARB.
Gene ID
209462
Gene Name (Vector)
HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1
Gene Symbol
Hace1
ORF Size (aa)
2730
ORF Size (bp)
2730 bp
RefSeq ID
NM_172473
RefSeq Synonyms
NM_172473, BC120697, BC120695,
Species
mouse
UniGene ID
Mm.458633

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.