mouse GRB2 Over-expression AAV
This is an AAV expressing Mouse Grb2.
AAV-260737
AAV-m-GRB2
Ready-to-use AAV expressing Mouse Grb2 (growth factor receptor bound protein 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AA408164; Ash
Description (Vector)
Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway|Function: Isoform 2 does not bind to phosphorylated epidermal growth factor receptor (EGFR) but inhibits EGF-induced transactivation of a RAS-responsive element. Isoform 2 acts as a dominant negative protein over GRB2 and by suppressing proliferative signals, may trigger active programmed cell death.
Gene ID
14784
Gene Name (Vector)
growth factor receptor bound protein 2
Gene Symbol
Grb2
ORF Size (aa)
654
ORF Size (bp)
654 bp
RefSeq ID
NM_008163
RefSeq Synonyms
NM_008163, NM_001313937, NM_001313936, BC085254, BC052377,
Species
mouse
UniGene ID
Mm.439649
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.