mouse BACE2 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-259759
Availability:
3-5 weeks
Name:
AAV-m-BACE2
This is an AAV expressing Mouse Bace2.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Bace2
- Gene Name
- beta-site APP-cleaving enzyme 2
- Gene ID
- 56175
- Gene Synonyms
- 1110059C24Rik; AEPLC; AI850424; ALP56; ARP1; ASP1; ASP21; BAE2; CDA13; CEAP1; DRAP
- ORF Size
- 1545 bp
- RefSeq#
- BC131947
- Gene Description
- Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.
- UniGene ID
- Mm.97885
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