mouse FRK Over-expression AAV

Name 
AAV-m-FRK
Cat No 
AAV-259629
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Frk.

AAV-259629
AAV-m-FRK

Ready-to-use AAV expressing Mouse Frk (fyn-related kinase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BSK; BSK/IYK; C85044; GTK; RAK
Description (Vector)
Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor.
Gene ID
14302
Gene Name (Vector)
fyn-related kinase
Gene Symbol
Frk
ORF Size (aa)
1539
ORF Size (bp)
1539 bp
RefSeq ID
NM_010237
RefSeq Synonyms
NM_010237, NM_001159544, BC007137,
Species
mouse
UniGene ID
Mm.441832

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.