mouse FRK shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Frk.
shADV-259629
Ad-m-FRK-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Frk (fyn-related kinase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BSK; BSK/IYK; C85044; GTK; RAK
Description (Vector)
Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor.
Gene ID
14302
Gene Name (Vector)
fyn-related kinase
Gene Symbol
Frk
ORF Size (aa)
1539
ORF Size (bp)
1539 bp
RefSeq ID
NM_010237
RefSeq Synonyms
NM_010237, NM_001159544, BC007137,
Species
mouse
UniGene ID
Mm.441832
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.