mouse FBLIM1 Over-expression AAV

Name 
AAV-m-FBLIM1
Cat No 
AAV-259183
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Fblim1.

AAV-259183
AAV-m-FBLIM1

Ready-to-use AAV expressing Mouse Fblim1 (filamin binding LIM protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2410043F08Rik; Cal; Fblp1; Gt10; migfilin; migfilin(s)
Description (Vector)
Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion.
Gene ID
74202
Gene Name (Vector)
filamin binding LIM protein 1
Gene Symbol
Fblim1
ORF Size (aa)
1128
ORF Size (bp)
1128 bp
RefSeq ID
NM_133754
RefSeq Synonyms
NM_133754, NM_001163256, BC004777,
Species
mouse
UniGene ID
Mm.286536

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.