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mouse FBLIM1 shRNA silencing Adenovirus

Name 
Ad-m-FBLIM1-shRNA
Cat No 
shADV-259183
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Fblim1.

shADV-259183
Ad-m-FBLIM1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Fblim1 (filamin binding LIM protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
2410043F08Rik; Cal; Fblp1; Gt10; migfilin; migfilin(s)
Description (Vector)
Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion.
Gene ID
74202
Gene Name (Vector)
filamin binding LIM protein 1
Gene Symbol
Fblim1
ORF Size (aa)
1128
ORF Size (bp)
1128 bp
RefSeq ID
NM_133754
RefSeq Synonyms
NM_133754, NM_001163256, BC004777,
Species
mouse
UniGene ID
Mm.286536

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.