mouse FADD Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-258879
Availability:
3-5 weeks
Name:
AAV-m-FADD
This is an AAV expressing Mouse Fadd.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Fadd
- Gene Name
- Fas (TNFRSF6)-associated via death domain
- Gene ID
- 14082
- Gene Synonyms
- Mort1/FADD
- ORF Size
- 618 bp
- RefSeq#
- BC021400
- Gene Description
- Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.
- UniGene ID
- Mm.5126
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