mouse ESRP2 Over-expression AAV

Name 
AAV-m-ESRP2
Cat No 
AAV-258719
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Esrp2.

AAV-258719
AAV-m-ESRP2

Ready-to-use AAV expressing Mouse Esrp2 (epithelial splicing regulatory protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
9530027K23Rik; Rbm35b
Description (Vector)
mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.
Gene ID
77411
Gene Name (Vector)
epithelial splicing regulatory protein 2
Gene Symbol
Esrp2
ORF Size (aa)
2154
ORF Size (bp)
2154 bp
RefSeq ID
NM_176838
RefSeq Synonyms
NM_176838, BC031444,
Species
mouse
UniGene ID
Mm.183003

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.