mouse ERI1 Over-expression AAV
This is an AAV expressing Mouse Eri1.
AAV-258662
AAV-m-ERI1
Ready-to-use AAV expressing Mouse Eri1 (exoribonuclease 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
3'hexo; 3110010F15Rik; eri-1; Thex1
Description (Vector)
RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.
Gene ID
67276
Gene Name (Vector)
exoribonuclease 1
Gene Symbol
Eri1
ORF Size (aa)
1038
RefSeq ID
NM_026067
RefSeq Synonyms
NM_026067, BC046412,
Species
mouse
UniGene ID
Mm.207534
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.