mouse ERCC2 Over-expression AAV

Name 
AAV-m-ERCC2
Cat No 
AAV-258632
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Ercc2.

AAV-258632
AAV-m-ERCC2

Ready-to-use AAV expressing Mouse Ercc2 (excision repair cross-complementing rodent repair deficiency, complementation group 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AA407812; AU020867; AW240756; CXPD; Ercc-2; Mhdarco15; RCO015; XPD
Description (Vector)
ATP-dependent 5'-3' DNA helicase, component of the core-TFIIH basal transcription factor. Involved in nucleotide excision repair (NER) of DNA by opening DNA around the damage, and in RNA transcription by RNA polymerase II by anchoring the CDK-activating kinase (CAK) complex, composed of CDK7, cyclin H and MAT1, to the core-TFIIH complex. Involved in the regulation of vitamin-D receptor activity. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation. Might have a role in aging process and could play a causative role in the generation of skin cancers.
Gene ID
13871
Gene Name (Vector)
excision repair cross-complementing rodent repair deficiency, complementation group 2
Gene Symbol
Ercc2
ORF Size (aa)
2220
ORF Size (bp)
2220 bp
RefSeq ID
NM_007949
RefSeq Synonyms
NM_007949, BC034517,
Species
mouse
UniGene ID
Mm.36524

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.