mouse CSNK1G2 Over-expression AAV
This is an AAV expressing Mouse Csnk1g2.
AAV-256248
AAV-m-CSNK1G2
Ready-to-use AAV expressing Mouse Csnk1g2 (casein kinase 1, gamma 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2810429I12Rik; AI463719
Description (Vector)
Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling (By similarity). Phosphorylates COL4A3BP/CERT, MTA1 and SMAD3. Involved in brain development and vesicular trafficking and neurotransmitter releasing from small synaptic vesicles. Regulates fast synaptic transmission mediated by glutamate. SMAD3 phosphorylation promotes its ligand-dependent ubiquitination and subsequent proteasome degradation, thus inhibiting SMAD3-mediated TGF-beta responses. Hyperphosphorylation of the serine-repeat motif of COL4A3BP/CERT leads to its inactivation by dissociation from the Golgi complex, thus down-regulating ER-to-Golgi transport of ceramide and sphingomyelin synthesis.
Gene ID
103236
Gene Name (Vector)
casein kinase 1, gamma 2
Gene Symbol
Csnk1g2
ORF Size (aa)
750
RefSeq ID
NM_134002
RefSeq Synonyms
NM_134002, NM_001159591, BC005750, BC004839,
Species
mouse
UniGene ID
Mm.29873
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.