mouse CDKN1B Over-expression AAV

Name 
AAV-m-CDKN1B
Cat No 
AAV-255188
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Cdkn1b.

AAV-255188
AAV-m-CDKN1B

Ready-to-use AAV expressing Mouse Cdkn1b (cyclin-dependent kinase inhibitor 1B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AA408329; AI843786; Kip1; p27; p27Kip1
Description (Vector)
Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.
Gene ID
12576
Gene Name (Vector)
cyclin-dependent kinase inhibitor 1B
Gene Symbol
Cdkn1b
ORF Size (aa)
594
RefSeq ID
NM_009875
RefSeq Synonyms
NM_009875, BC014296,
Species
mouse
UniGene ID
Mm.2958

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.