mouse CD33 Over-expression AAV

Name
AAV-m-CD33

Cat No
AAV-255000

Availability
4-5 weeks

Categories
AAV, Over-Expression

This is an AAV expressing Mouse Cd33.

AAV-255000

AAV-m-CD33

Ready-to-use AAV expressing Mouse Cd33 (CD33 antigen). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

gp67; Siglec-3

Description (Vector)

Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).

Gene ID

12489

Gene Name (Vector)

CD33 antigen

Gene Symbol

Cd33

ORF Size (aa)

1005

ORF Size (bp)

1005 bp

RefSeq ID

NM_021293

RefSeq Synonyms

NM_021293, NM_001111058, BC132379,

Species

mouse

UniGene ID

Mm.140157

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.