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mouse CD33 shRNA silencing Adenovirus

Name 
Ad-m-CD33-shRNA
Cat No 
shADV-255000
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Cd33.

shADV-255000
Ad-m-CD33-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Cd33 (CD33 antigen). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
gp67; Siglec-3
Description (Vector)
Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).
Gene ID
12489
Gene Name (Vector)
CD33 antigen
Gene Symbol
Cd33
ORF Size (aa)
1005
ORF Size (bp)
1005 bp
RefSeq ID
NM_021293
RefSeq Synonyms
NM_021293, NM_001111058, BC132379,
Species
mouse
UniGene ID
Mm.140157

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.