mouse CCNT1 Over-expression AAV

Name
AAV-m-CCNT1

Cat No
AAV-254888

Availability
4-5 weeks

Categories
AAV, Over-Expression

This is an AAV expressing Mouse Ccnt1.

AAV-254888

AAV-m-CCNT1

Ready-to-use AAV expressing Mouse Ccnt1 (cyclin T1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

2810478G24Rik; AI115585; CycT1

Description (Vector)

Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to productive elongation by phosphorylating the CTD (carboxy-terminal domain) of the large subunit of RNA polymerase II (RNA Pol II). In case of HIV or SIV infections, binds to the transactivation domain of the viral nuclear transcriptional activator, Tat, thereby increasing Tat's affinity for the transactivating response RNA element (TAR RNA). Serves as an essential cofactor for Tat, by promoting RNA Pol II activation, allowing transcription of viral genes.

Gene ID

12455

Gene Name (Vector)

cyclin T1

Gene Symbol

Ccnt1

ORF Size (aa)

2175

ORF Size (bp)

2175 bp

RefSeq ID

NM_009833

RefSeq Synonyms

NM_009833, BC131685,

Species

mouse

UniGene ID

Mm.86538

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.