mouse CASP1 Over-expression AAV

Name 
AAV-m-CASP1
Cat No 
AAV-254551
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Casp1.

AAV-254551
AAV-m-CASP1

Ready-to-use AAV expressing Mouse Casp1 (caspase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ICE; Il1bc
Description (Vector)
Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.
Gene ID
12362
Gene Name (Vector)
caspase 1
Gene Symbol
Casp1
ORF Size (aa)
1209
RefSeq ID
NM_009807
RefSeq Synonyms
NM_009807, BC008152,
Species
mouse
UniGene ID
Mm.1051

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.