mouse BCL2 Over-expression AAV

Name
AAV-m-BCL2

Cat No
AAV-253879

Availability
4-5 weeks

This is an AAV expressing Mouse Bcl2.

AAV-253879

AAV-m-BCL2

Ready-to-use AAV expressing Mouse Bcl2 (B cell leukemia/lymphoma 2). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AW986256; Bcl-2; C430015F12Rik; D630044D05Rik; D830018M01Rik

Description (Vector)

Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).

Gene ID

12043

Gene Name (Vector)

B cell leukemia/lymphoma 2

Gene Symbol

Bcl2

ORF Size (aa)

711

RefSeq ID

NM_009741

RefSeq Synonyms

NM_177410, NM_009741, BC095964, BC068988,

Species

mouse

UniGene ID

Mm.477249

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.