mouse BCL2 Over-expression AAV

Name 
AAV-m-BCL2
Cat No 
AAV-253879
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Bcl2.

AAV-253879
AAV-m-BCL2

Ready-to-use AAV expressing Mouse Bcl2 (B cell leukemia/lymphoma 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AW986256; Bcl-2; C430015F12Rik; D630044D05Rik; D830018M01Rik
Description (Vector)
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
Gene ID
12043
Gene Name (Vector)
B cell leukemia/lymphoma 2
Gene Symbol
Bcl2
ORF Size (aa)
711
RefSeq ID
NM_009741
RefSeq Synonyms
NM_177410, NM_009741, BC095964, BC068988,
Species
mouse
UniGene ID
Mm.477249

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.