mouse ATXN1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-253377
Availability:
3-5 weeks
Name:
AAV-m-ATXN1
This is an AAV expressing Mouse Atxn1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Atxn1
- Gene Name
- ataxin 1
- Gene ID
- 20238
- Gene Synonyms
- 2900016G23Rik; Atx1; C85907; ENSMUSG00000074917; Gm10786; Sca1
- ORF Size
- 2376 bp
- RefSeq#
- BC058178
- Gene Description
- Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism. The expansion of the polyglutamine tract may alter this function.
- UniGene ID
- Mm.476983
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