mouse ATXN1 Over-expression AAV

Name 
AAV-m-ATXN1
Cat No 
AAV-253377
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Atxn1.

AAV-253377
AAV-m-ATXN1

Ready-to-use AAV expressing Mouse Atxn1 (ataxin 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2900016G23Rik; Atx1; C85907; ENSMUSG00000074917; Gm10786; Sca1
Description (Vector)
Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism. The expansion of the polyglutamine tract may alter this function.
Gene ID
20238
Gene Name (Vector)
ataxin 1
Gene Symbol
Atxn1
ORF Size (aa)
2376
ORF Size (bp)
2376 bp
RefSeq ID
NM_009124
RefSeq Synonyms
NM_009124, NM_001199305, NM_001199304, BC058178,
Species
mouse
UniGene ID
Mm.476983

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.