mouse ATXN1 shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-253377
Availability:
4-5 weeks
Name:
AAV-m-ATXN1-shRNA
This is an AAV expressing shRNA for silencing of Mouse Atxn1.
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Product Info
- Knockdown
- >60% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Atxn1
- Gene Name
- ataxin 1
- Gene ID
- 20238
- Gene Synonyms
- 2900016G23Rik; Atx1; C85907; ENSMUSG00000074917; Gm10786; Sca1
- ORF Size
- 2376 bp
- RefSeq#
- NM_009124
- Gene Description
- Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism. The expansion of the polyglutamine tract may alter this function.
- UniGene ID
- Mm.476983
Related Products
Product | Cat No. |
---|---|
AAV-h-ATXN1 | AAV-229176 |
AAV-m-ATXN1 | AAV-253377 |
Ad-h-ATXN1 | ADV-229176 |
Ad-m-ATXN1 | ADV-253377 |
AAV-h-ATXN1-shRNA | shAAV-229176 |
Ad-h-ATXN1-shRNA | shADV-229176 |
Ad-m-ATXN1-shRNA | shADV-253377 |
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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