mouse ARPP19 Over-expression AAV

Name 
AAV-m-ARPP19
Cat No 
AAV-253075
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Arpp19.

AAV-253075
AAV-m-ARPP19

Ready-to-use AAV expressing Mouse Arpp19 (cAMP-regulated phosphoprotein 19). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
19kDa; 2700024H10Rik; ARPP-19; Arpp12; AW559096
Description (Vector)
Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. May indirectly enhance GAP-43 expression.
Gene ID
59046
Gene Name (Vector)
cAMP-regulated phosphoprotein 19
Gene Symbol
Arpp19
ORF Size (aa)
339
RefSeq ID
NM_021548
RefSeq Synonyms
NM_021548, NM_001142655, BC040206,
Species
mouse
UniGene ID
Mm.247837

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.