mouse ARL3 Over-expression AAV
This is an AAV expressing Mouse Arl3.
AAV-253015
AAV-m-ARL3
Ready-to-use AAV expressing Mouse Arl3 (ADP-ribosylation factor-like 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). Required for normal cytokinesis and cilia signaling. Requires assistance from GTPase-activating proteins (GAPs) like RP2 and PDE6D, in order to cycle between inactive GDP-bound and active GTP-bound forms. Required for targeting proteins such as NPHP3 to the ciliary membrane by releasing myristoylated NPHP3 from UNC119B cargo adapter into the cilium. Does not act as an allosteric activator of the cholera toxin catalytic subunit.
Gene ID
56350
Gene Name (Vector)
ADP-ribosylation factor-like 3
Gene Symbol
Arl3
ORF Size (aa)
549
RefSeq ID
NM_019718
RefSeq Synonyms
NM_019718, BC042941,
Species
mouse
UniGene ID
Mm.22085
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.