mouse ARHGEF1 Over-expression AAV
This is an AAV expressing Mouse Arhgef1.
AAV-252962
AAV-m-ARHGEF1
Ready-to-use AAV expressing Mouse Arhgef1 (Rho guanine nucleotide exchange factor (GEF) 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Lbcl2; Lsc
Description (Vector)
Seems to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13) subunits. Acts as GTPase-activating protein (GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor (GEF) for RhoA GTPase. Activated G alpha 13/GNA13 stimulates the RhoGEF activity through interaction with the RGS-like domain. This GEF activity is inhibited by binding to activated GNA12. Mediates angiotensin-2-induced RhoA activation.
Gene ID
16801
Gene Name (Vector)
Rho guanine nucleotide exchange factor (GEF) 1
Gene Symbol
Arhgef1
ORF Size (aa)
2763
ORF Size (bp)
2763 bp
RefSeq ID
NM_008488
RefSeq Synonyms
NM_008488, NM_001130153, NM_001130152, NM_001130151, NM_001130150, BC012488,
Species
mouse
UniGene ID
Mm.3181
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.