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mouse ACPP Over-expression AAV

Name 
AAV-m-ACPP
Cat No 
AAV-251953
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Acpp.

AAV-251953
AAV-m-ACPP

Ready-to-use AAV expressing Mouse Acpp (acid phosphatase, prostate). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
5'-NT; A030005E02Rik; FRAP; Lap; PAP; Ppal
Description (Vector)
A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions (pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma|Function: Isoform 2: the cellular form also has ecto-5'-nucleotidase activity in dorsal root ganglion (DRG) neurons. Generates adenosine from AMP which acts as a pain suppressor. Acts as a tumor suppressor of prostate cancer through dephosphorylation of ERBB2 and deactivation of MAPK-mediated signaling.
Gene ID
56318
Gene Name (Vector)
acid phosphatase, prostate
Gene Symbol
Acpp
ORF Size (aa)
1254
ORF Size (bp)
1254 bp
RefSeq ID
NM_019807
RefSeq Synonyms
NM_207668, NM_019807, BC139826,
Species
mouse
UniGene ID
Mm.19941

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.