mouse SGMS2 Over-expression AAV

Name 
AAV-m-SGMS2
Cat No 
AAV-251330
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Sgms2.

AAV-251330
AAV-m-SGMS2

Ready-to-use AAV expressing Mouse Sgms2 (sphingomyelin synthase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
4933405A16Rik; 5133401H06Rik; AI854299
Description (Vector)
Bidirectional lipid cholinephosphotransferase capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and vice versa. Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. Directly and specifically recognizes the choline head group on the substrate. Also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Does not function strictly as a SM synthase. Required for cell growth.
Gene ID
74442
Gene Name (Vector)
sphingomyelin synthase 2
Gene Symbol
Sgms2
ORF Size (aa)
1098
ORF Size (bp)
1098 bp
RefSeq ID
NM_028943
RefSeq Synonyms
NM_028943, BC117782,
Species
mouse
UniGene ID
Mm.273360

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.