mouse GLYR1 Over-expression AAV

Cat. No: AAV-250956

Availability: 3-5 weeks

Name: AAV-m-GLYR1

This is an AAV expressing Mouse Glyr1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Glyr1
Gene Name: glyoxylate reductase 1 homolog (Arabidopsis)
Gene ID: 74022
Gene Synonyms: 2810419J22Rik; 3930401K13Rik; AW545332; Npac
ORF Size: 1641 bp
RefSeq#: BC006893
Gene Description: GLYR1 may have oxidoreductase activity. Regulates p38 MAP kinase activity by mediating stress activation of p38alpha/MAPK14 and specifically regulating MAPK14 signaling. Indirectly promotes phosphorylation of MAPK14 and activation of ATF2. The phosphorylation of MAPK14 requires upstream activity of MAP2K4 and MAP2K6. Recruited on chromatin, recognizes and binds trimethylated 'Lys-36' of histone H3 (H3K36me3).
UniGene ID: Mm.21652