mouse 2010110P09RIK Over-expression AAV

Name 
AAV-m-2010110P09RIK
Cat No 
AAV-250556
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Chp2.

AAV-250556
AAV-m-2010110P09RIK

Ready-to-use AAV expressing Mouse Chp2 (calcineurin-like EF hand protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2010110P09Rik; Cbhp2
Description (Vector)
Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity. Binds to and activates SLC9A1/NHE1 in a serum-independent manner, thus increasing pH and protecting cells from serum deprivation-induced death. Also plays a role in the regulation of cell proliferation and tumor growth by increasing the phosphatase activity of PPP3CA in a calcium-dependent manner. Activator of the calcineurin/NFAT signaling pathway. Involved in the cytoplasmic translocation of the transcription factor NFATC3 to the nucleus.
Gene ID
70261
Gene Name (Vector)
calcineurin-like EF hand protein 2
Gene Symbol
Chp2
ORF Size (aa)
591
RefSeq ID
NM_027363
RefSeq Synonyms
NM_027363, BC119204, BC119202,
Species
mouse
UniGene ID
Mm.96997

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.