human HGF Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-233950
Availability:
3-5 weeks
Name:
AAV-h-HGF
This is an AAV expressing Human HGF.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- HGF
- Gene Name
- hepatocyte growth factor
- Gene ID
- 3082
- Gene Synonyms
- DFNB39; F-TCF; HGFB; HPTA; SF
- ORF Size
- 2187 bp
- RefSeq#
- BC063485
- Gene Description
- Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms.
- UniGene ID
- Hs.396530
- HGNC ID
- HGNC:4893
Related Products
Product | Cat No. |
---|---|
AAV-m-HGF | AAV-261273 |
Ad-h-HGF | ADV-233950 |
Ad-m-HGF | ADV-261273 |
AAV-h-HGF-shRNA | shAAV-210994 |
AAV-m-HGF-shRNA | shAAV-261273 |
Ad-h-HGF-shRNA | shADV-210994 |
Ad-m-HGF-shRNA | shADV-261273 |
Control Products
Vector Biolabs
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Malvern, PA 19355
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