human MAPT Over-expression AAV

Name 
AAV-h-MAPT
Cat No 
AAV-233559
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human MAPT.

AAV-233559
AAV-h-MAPT

Ready-to-use AAV expressing Human MAPT (microtubule associated protein tau). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; TAU
Description (Vector)
MAPT encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
Gene ID
4137
Gene Name (Vector)
microtubule associated protein tau
Gene Symbol
MAPT
HGNC ID
HGNC:6893
ORF Size (aa)
1152
ORF Size (bp)
1152 bp
RefSeq ID
NM_005910
RefSeq Synonyms
NM_016841, NM_016835, NM_016834, NM_005910, NM_001203252, NM_001203251, NM_001123067, NM_001123066, BC114948,
Species
human

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.