human A2LD1 Over-expression AAV

Name
AAV-h-A2LD1

Cat No
AAV-233323

Availability
4-5 weeks

This is an AAV expressing Human GGACT.

AAV-233323

AAV-h-A2LD1

Ready-to-use AAV expressing Human GGACT (gamma-glutamylamine cyclotransferase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

A2LD1

Description (Vector)

A2LD1 aids in the proteolytic degradation of crosslinked fibrin by breaking down isodipeptide L-gamma-glutamyl-L-epsilon-lysine, a byproduct of fibrin degradation. The reaction catalyzed by the encoded gamma-glutamylaminecyclotransferase produces 5-oxo-L-proline and a free alkylamine. Two transcript variants encoding the same protein have been found for this gene.

Gene ID

87769

Gene Name (Vector)

gamma-glutamylamine cyclotransferase

Gene Symbol

GGACT

HGNC ID

HGNC:25100

ORF Size (aa)

462

ORF Size (bp)

462 bp

RefSeq ID

NM_033110

RefSeq Synonyms

NM_033110, NM_001195087, BC001077,

Species

human

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.