human PLEKHG2 Over-expression AAV

Name 
AAV-h-PLEKHG2
Cat No 
AAV-232804
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PLEKHG2.

AAV-232804
AAV-h-PLEKHG2

Ready-to-use AAV expressing Human PLEKHG2 (pleckstrin homology and RhoGEF domain containing G2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ARHGEF42; CLG; common-site lymphoma/leukemia guanine nucleotide exchange factor; CTB-60E11.4; LDAMD; PH domain-containing family G member 2; pleckstrin homology domain containing, family G (with RhoGef domain) member 2; pleckstrin homology domain-containing family G member 2
Description (eCommerce)
PLEKHG2 (pleckstrin homology domain-containing family G member 2) contains a RhoGEF/DH domain and a pleckstrin homology (PH) domain. PH domains are found in proteins involved in cell signaling. PLEKHG2 is proposed to be a guanine-nucleotide exchange factor (GEF) for RAC1/CDC42.
Gene ID
64857
Gene Name (eCommerce)
pleckstrin homology and RhoGEF domain containing G2
Gene Name (Vector)
pleckstrin homology and RhoGEF domain containing G2
Gene Symbol
PLEKHG2
HGNC ID
HGNC:29515
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2977
ORF Size (bp)
2977 bp
Protein Name (eCommerce)
Pleckstrin homology domain-containing family G member 2
RefSeq ID
NM_022835
RefSeq Synonyms
NM_022835, BC013426,
Research Areas
Apoptosis,Cancer,GPCR Signaling,Neurobiology,NGF Signaling,Rho Signaling,Signal Transduction,Tumor Suppressors/Oncoproteins
Research Areas (Faceted)
cancer,cell_biology,neurobiology,signal_transduction
Species
human
Target Sentence
PLEKHG2 (pleckstrin homology domain-containing family G member 2) contains a RhoGEF/DH domain and a pleckstrin homology (PH) domain. PH domains are found in proteins involved in cell signaling. PLEKHG2 is proposed to be a guanine-nucleotide exchange factor (GEF) for RAC1/CDC42.
UniProt ID (eCommerce)
Q9H7P9

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.