human CYP3A43 Over-expression AAV

Name
AAV-h-CYP3A43

Cat No
AAV-232744

Availability
4-5 weeks

This is an AAV expressing Human CYP3A43.

AAV-232744

AAV-h-CYP3A43

Ready-to-use AAV expressing Human CYP3A43 (cytochrome P450 family 3 subfamily A member 43). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

CYP3A43 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme has a low level of testosterone hydroxylase activity. Although it bears homology to some drug-metabolizing cytochrome P450s, it is unknown whether the enzyme is also involved in xenobiotic metabolism. CYP3A43 is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Alternate splicing of this gene results in three transcript variants encoding different isoforms.

Gene ID

64816

Gene Name (Vector)

cytochrome P450 family 3 subfamily A member 43

Gene Symbol

CYP3A43

HGNC ID

HGNC:17450

ORF Size (aa)

1182

ORF Size (bp)

1182 bp

RefSeq ID

NM_022820

RefSeq Synonyms

NM_057096, NM_057095, NM_022820, NM_001278921, BC100982, BC100981,

Species

human

UniGene ID

Hs.306220

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.