human XRCC3 Over-expression AAV

Name 
AAV-h-XRCC3
Cat No 
AAV-231453
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human XRCC3.

AAV-231453
AAV-h-XRCC3

Ready-to-use AAV expressing Human XRCC3 (X-ray repair cross complementing 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CMM6
Description (Vector)
XRCC3 encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. XRCC3 functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified.
Gene ID
7517
Gene Name (Vector)
X-ray repair cross complementing 3
Gene Symbol
XRCC3
HGNC ID
HGNC:12830
ORF Size (aa)
1041
RefSeq ID
NM_005432
RefSeq Synonyms
NM_005432, NM_001100119, NM_001100118, BC011725, BC001036,
Species
human
UniGene ID
Hs.719391

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.