human MICB Over-expression AAV

Name 
AAV-h-MICB
Cat No 
AAV-231124
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human MICB.

AAV-231124
AAV-h-MICB

Ready-to-use AAV expressing Human MICB (MHC class I polypeptide-related sequence B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
PERB11.2
Description (Vector)
MICB encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides.
Gene ID
4277
Gene Name (Vector)
MHC class I polypeptide-related sequence B
Gene Symbol
MICB
HGNC ID
HGNC:7091
ORF Size (aa)
1023
ORF Size (bp)
1023 bp
RefSeq ID
NM_005931
RefSeq Synonyms
NM_005931, NM_001289161, NM_001289160, BC044218,
Species
human
UniGene ID
Hs.

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.