human S1PR1 Over-expression AAV

Name
AAV-h-S1PR1

Cat No
AAV-230289

Availability
4-5 weeks

This is an AAV expressing Human S1PR1.

AAV-230289

AAV-h-S1PR1

Ready-to-use AAV expressing Human S1PR1 (sphingosine-1-phosphate receptor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CD363; CHEDG1; D1S3362; ECGF1; EDG-1; EDG1; S1P1

Description (Vector)

S1PR1 is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion.

Gene ID

1901

Gene Name (Vector)

sphingosine-1-phosphate receptor 1

Gene Symbol

S1PR1

HGNC ID

HGNC:3165

ORF Size (aa)

1149

ORF Size (bp)

1149 bp

RefSeq ID

NM_001400

RefSeq Synonyms

NM_001400, NM_001320730, BC018650,

Species

human

UniGene ID

Hs.154210

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.