human GRINL1A Over-expression AAV

Name 
AAV-h-GRINL1A
Cat No 
AAV-229837
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human POLR2M.

AAV-229837
AAV-h-GRINL1A

Ready-to-use AAV expressing Human POLR2M (RNA polymerase II subunit M). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GCOM1; Gdown; Gdown1; GRINL1A
Description (Vector)
POLR2M encodes a subunit of RNA polymerase II, a protein complex that is responsible for synthesizing messenger RNA in eukaryotes. The encoded protein functions as a component of a specific form of RNA polymerase II termed Pol II(G). This protein may act as a negative regulator of activator-dependent transcription. Alternate splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream gene MYZAP (myocardial zonula adherens protein).
Gene ID
81488
Gene Name (Vector)
RNA polymerase II subunit M
Gene Symbol
POLR2M
HGNC ID
HGNC:14862
ORF Size (aa)
1107
ORF Size (bp)
1107 bp
RefSeq ID
NM_015532
RefSeq Synonyms
NM_015532, NM_001018102, BC001510,
Species
human
UniGene ID
Hs.

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.