human ZNRF2 Over-expression AAV

Name 
AAV-h-ZNRF2
Cat No 
AAV-228966
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ZNRF2.

AAV-228966
AAV-h-ZNRF2

Ready-to-use AAV expressing Human ZNRF2 (zinc and ring finger 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
E3 ubiquitin-protein ligase ZNRF2; protein Ells2; RING finger protein 202; RING-type E3 ubiquitin transferase ZNRF2; RNF202; zinc and ring finger 2, E3 ubiquitin protein ligase; zinc finger/RING finger 2; zinc/RING finger protein 2
Description (eCommerce)
Zinc- and RING- finger 2 (ZNRF2) is suggested to play a role in the establisment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8NHG8].
Gene ID
223082
Gene Name (eCommerce)
zinc and ring finger 2
Gene Name (Vector)
zinc and ring finger 2
Gene Symbol
ZNRF2
HGNC ID
HGNC:22316
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
729
ORF Size (bp)
729 bp
Protein Name (eCommerce)
E3 ubiquitin-protein ligase ZNRF2
RefSeq ID
NM_147128
RefSeq Synonyms
NM_147128, BC172400,
Research Areas
Lysosome,Neurobiology,Synapse,Ubiquitination,Zinc-finger
Research Areas (Faceted)
cell_biology,neurobiology
Species
human
Target Sentence
Zinc- and RING- finger 2 (ZNRF2) is suggested to play a role in the establisment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8NHG8].
UniGene ID
Hs.487869
UniProt ID (eCommerce)
Q8NHG8

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.