human YWHAQ Over-expression AAV

Name 
AAV-h-YWHAQ
Cat No 
AAV-228006
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human YWHAQ.

AAV-228006
AAV-h-YWHAQ

Ready-to-use AAV expressing Human YWHAQ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
14-3-3; 14-3-3 protein tau; 14-3-3 protein T-cell; 14-3-3 protein theta; 14-3-3 theta; 1C5; HS1; Protein HS1; protein, theta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
Description (eCommerce)
14-3-3 theta is a member of the 14-3-3 family of proteins which serve as adapter proteins in specialized signal transduction pathways. There are 7 members of the 14-3-3 family of proteins: beta, gamma, epsilon, zeta, eta, theta, and sigma.
Description (Vector)
YWHAQ product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. YWHAQ is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.
Gene ID
10971
Gene Name (eCommerce)
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
Gene Name (Vector)
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
Gene Symbol
YWHAQ
HGNC ID
HGNC:12854
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
738
Protein Name (eCommerce)
14-3-3 protein theta
RefSeq ID
NM_006826
RefSeq Synonyms
NM_006826, BC093019, BC056867, BC050601,
Research Areas
Apoptosis,Cancer,Cardiology,Cardiovascular,CD95/FAS Signaling,Cell Cycle,EPO Signaling,FGF Signaling,FoxO Signaling,Hippo Signaling,Host-Virus Interactions,Immunology,Interleukin Signaling,LKB1 Signaling,MAPK Signaling,Meiosis,mTOR Signaling,NFAT Signaling,PDGF Signaling,PI3K/Akt Signaling,Signal Transduction,T-cell Receptor Signaling,TNF Signaling,Transcription Factor/Regulator,Viral Carcinogenesis
Research Areas (Faceted)
cancer,cardiovascular,cell_biology,cell_cycle,developmental_biology,genetics,immunology,infectious_disease,signal_transduction,transcription_translation
Species
human
Target Sentence
14-3-3 theta is a member of the 14-3-3 family of proteins which serve as adapter proteins in specialized signal transduction pathways. There are 7 members of the 14-3-3 family of proteins: beta, gamma, epsilon, zeta, eta, theta, and sigma.
UniGene ID
Hs.74405
UniProt ID (eCommerce)
P27348

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.